Anti-KLK7 antibody [SAA0869] (STJA0019664)

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STJA0019664
£378.50 - £1,632.50
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Host: Mouse
Applications: Blocking/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Kallikrein-7 is suitable for use in Universaling and ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA0869
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: KLK7
Gene ID: 5650
Uniprot ID: KLK7_HUMAN
Function May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Protein Name Kallikrein-7
Hk7
Serine Protease 6
Stratum Corneum Chymotryptic Enzyme
Hscce
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-9725554
Cellular Localisation Secreted
In Ovarian Carcinoma
Secreted And Also Observed At The Apical Membrane And In Cytoplasm At The Invasive Front
Alternative Antibody Names Anti-Kallikrein-7 antibody
Anti-Hk7 antibody
Anti-Serine Protease 6 antibody
Anti-Stratum Corneum Chymotryptic Enzyme antibody
Anti-Hscce antibody
Anti-KLK7 antibody
Anti-PRSS6 antibody
Anti-SCCE antibody

Information sourced from Uniprot.org