Function | May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. |
Protein Name | Kallikrein-7Hk7Serine Protease 6Stratum Corneum Chymotryptic EnzymeHscce |
Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-9725554 |
Cellular Localisation | SecretedIn Ovarian CarcinomaSecreted And Also Observed At The Apical Membrane And In Cytoplasm At The Invasive Front |
Alternative Antibody Names | Anti-Kallikrein-7 antibodyAnti-Hk7 antibodyAnti-Serine Protease 6 antibodyAnti-Stratum Corneum Chymotryptic Enzyme antibodyAnti-Hscce antibodyAnti-KLK7 antibodyAnti-PRSS6 antibodyAnti-SCCE antibody |
Information sourced from Uniprot.org