| Short Description : | Rabbit polyclonal KLHL8 (271-620) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLHL8 |
| Gene ID: | 57563 |
| Uniprot ID: | KLHL8_HUMAN |
| Immunogen Region: | 271-620 |
| Immunogen Sequence: | AKEQIVKQNLKCRDLLDEAR NYHLHLSSRAVPDFEYSIRT TPRKHTAGVLFCVGGRGGSG DPFRSIECYSINKNSWFFGP EMNSRRRHVGVISVEGKVYA VGGHDGNEHLGSMEMFDPLT NKWMMKASMNTKRRGIALAS LGGPIYAIGGLDDNTCFNDV ERYDIESDQWSTVAPMNTPR GGVGSVALVNHVYAVGGNDG MASLSSVERYDPHLDKWIEV KEMGQRRAGNGVSKLHGCL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 271-620 of human KLHL8 (NP_065854.3). |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. |
| Protein Name | Kelch-Like Protein 8 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kelch-Like Protein 8 antibodyAnti-KLHL8 antibodyAnti-KIAA1378 antibody |
Information sourced from Uniprot.org
