| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF17 |
| Gene ID: | 128209 |
| Uniprot ID: | KLF17_HUMAN |
| Immunogen Region: | 210-389 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3). |
| Immunogen Sequence: | QMLPPQDAHDLGMPPAESQS LLVLGSQDSLVSQPDSQEGP FLPEQPGPAPQTVEKNSRPQ EGTGRRGSSEARPYCCNYEN CGKAYTKRSHLVSHQRKHTG ERPYSCNWESCSWSFFRSDE LRRHMRVHTRYRPYKCDQCS REFMRSDHLKQHQKTHRPGP SDPQANNNNGEQDSPPAAGP |
| Function | Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
| Protein Name | Krueppel-Like Factor 17Zinc Finger Protein 393 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 17 antibodyAnti-Zinc Finger Protein 393 antibodyAnti-KLF17 antibodyAnti-ZNF393 antibody |
Information sourced from Uniprot.org