| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KLF17 (210-389) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLF17 |
| Gene ID: |
128209 |
| Uniprot ID: |
KLF17_HUMAN |
| Immunogen Region: |
210-389 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3). |
| Immunogen Sequence: |
QMLPPQDAHDLGMPPAESQS LLVLGSQDSLVSQPDSQEGP FLPEQPGPAPQTVEKNSRPQ EGTGRRGSSEARPYCCNYEN CGKAYTKRSHLVSHQRKHTG ERPYSCNWESCSWSFFRSDE LRRHMRVHTRYRPYKCDQCS REFMRSDHLKQHQKTHRPGP SDPQANNNNGEQDSPPAAGP |
| Function | Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
| Protein Name | Krueppel-Like Factor 17Zinc Finger Protein 393 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 17 antibodyAnti-Zinc Finger Protein 393 antibodyAnti-KLF17 antibodyAnti-ZNF393 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
