Anti-KLF15 antibody [2G8] (STJ98198)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human KLF15 expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Krueppel-like factor 15 for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2G8 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF15 |
| Gene ID | 28999 |
| Uniprot ID | KLF15_HUMAN |
| Immunogen | Purified recombinant fragment of human KLF15 expressed in E. Coli. |
| Specificity | KLF15 Monoclonal Antibody detects endogenous levels of KLF15 protein. |
Additional Info
| Function | Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart. Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4. Involved in podocyte differentiation. Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation. |
| Protein Name | Krueppel-Like Factor 15Kidney-Enriched Krueppel-Like Factor |
| Database Links | Reactome: R-HSA-1368108 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 15 antibodyAnti-Kidney-Enriched Krueppel-Like Factor antibodyAnti-KLF15 antibodyAnti-KKLF antibody |
Information sourced from Uniprot.org