| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIR3DS1 |
| Gene ID: | 3813 |
| Uniprot ID: | KI3S1_HUMAN |
| Immunogen Region: | 80-340 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_001077008.1). |
| Immunogen Sequence: | FNMSPVTTAHAGNYTCRGSH PHSPTGWSAPSNPMVIMVTG NHRKPSLLAHPGPLVKSGER VILQCWSDIMFEHFFLHKEW ISKDPSRLVGQIHDGVSKAN FSIGSMMRALAGTYRCYGSV THTPYQLSAPSDPLDIVVTG LYEKPSLSAQPGPKVQAGES VTLSCSSRSSYDMYHLSREG GAHERRLPAVRKVNRTFQAD FPLGPATHGGTYRCFGSFRH SPYEWSDPSDPLLVSVTGN |
| Tissue Specificity | Expressed in NK and T-cell lines but not in B-lymphoblastoid cell lines or in a colon carcinoma cell line. |
| Function | Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3ds1Natural Killer-Associated Transcript 10Nkat-10 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3ds1 antibodyAnti-Natural Killer-Associated Transcript 10 antibodyAnti-Nkat-10 antibodyAnti-KIR3DS1 antibodyAnti-NKAT10 antibody |
Information sourced from Uniprot.org