| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIFAP3 |
| Gene ID: | 22920 |
| Uniprot ID: | KIFA3_HUMAN |
| Immunogen Region: | 675-792 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845). |
| Immunogen Sequence: | KFRWHNSQWLEMVESRQMDE SEQYLYGDDRIEPYIHEGDI LERPDLFYNSDGLIASEGAI SPDFFNDYHLQNGDVVGQHS FPGSLGMDGFGQPVGILGRP ATAYGFRPDEPYYYGYGS |
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC in vitro.this reduces the binding affinity of the protein for RAP1GDS1. |
| Function | Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex. |
| Protein Name | Kinesin-Associated Protein 3Kap-3Kap3Smg Gds-Associated Protein |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2132295Reactome: R-HSA-5620924Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Alternative Antibody Names | Anti-Kinesin-Associated Protein 3 antibodyAnti-Kap-3 antibodyAnti-Kap3 antibodyAnti-Smg Gds-Associated Protein antibodyAnti-KIFAP3 antibodyAnti-KIF3AP antibodyAnti-SMAP antibody |
Information sourced from Uniprot.org