| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF1B (1501-1770) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF1B |
| Gene ID: |
23095 |
| Uniprot ID: |
KIF1B_HUMAN |
| Immunogen Region: |
1501-1770 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1501-1770 of human KIF1B (NP_055889.2). |
| Immunogen Sequence: |
SQISTTTFESAITPSESSGY DSGDIESLVDREKELATKCL QLLTHTFNREFSQVHGSVSD CKLSDISPIGRDPSESSFSS ATLTPSSTCPSLVDSRSNSL DQKTPEANSRASSPCPEFEQ FQIVPAVETPYLARAGKNEF LNLVPDIEEIRPSSVVSKKG YLHFKEPLYSNWAKHFVVVR RPYVFIYNSDKDPVERGIIN LSTAQVEYSEDQQAMVKTPN TFAVCTKHRGVLLQALNDK |
| Tissue Specificity | Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas. |
| Function | Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. Isoform 1 mediates the transport of synaptic vesicles in neuronal cells. |
| Protein Name | Kinesin-Like Protein Kif1bKlp |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonMitochondrionCell ProjectionAxonIsoform 1: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif1b antibodyAnti-Klp antibodyAnti-KIF1B antibodyAnti-KIAA0591 antibodyAnti-KIAA1448 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
