| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Kinesin-like protein KIF18A (713-763 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIF18A |
| Gene ID: | 81930 |
| Uniprot ID: | KI18A_HUMAN |
| Immunogen Region: | 713-763 aa |
| Specificity: | This antibody detects endogenous levels of KI18A at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human KI18A at the amino acid range 713-763 |
| Function | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| Protein Name | Kinesin-Like Protein Kif18a Marrow Stromal Kif18a Ms-Kif18a |
| Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-2132295 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-6811434 Reactome: R-HSA-68877 Reactome: R-HSA-9648025 Reactome: R-HSA-983189 |
| Cellular Localisation | Cell Projection Ruffle Cytoplasm Nucleus Cytoskeleton Microtubule Organizing Center Centrosome |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif18a antibody Anti-Marrow Stromal Kif18a antibody Anti-Ms-Kif18a antibody Anti-KIF18A antibody Anti-OK antibody Anti-SW-cl.108 antibody |
Information sourced from Uniprot.org