Anti-KIF13B antibody (111-160 aa) (STJ93834)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KIF13B at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-Kinesin-like protein KIF13B (111-160 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIF13B |
| Gene ID | 23303 |
| Uniprot ID | KI13B_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human KIF13B at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | KIF13B Polyclonal Antibody detects endogenous levels of KIF13B protein. |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-1381 and Ser-1410 by MARK2, promoting interaction with 14-3-3 and inhibiting microtubule-dependent accumulation and formation of axons. |
| Function | Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes. |
| Protein Name | Kinesin-Like Protein Kif13bKinesin-Like Protein Gakin |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxonAccumulates At The Distal Part Of The Microtubules In The Tips Of AxonsBut Not Of Dendrites |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif13b antibodyAnti-Kinesin-Like Protein Gakin antibodyAnti-KIF13B antibodyAnti-GAKIN antibodyAnti-KIAA0639 antibody |
Information sourced from Uniprot.org