| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein TALPID3 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIAA0586 |
| Gene ID: |
9786 |
| Uniprot ID: |
TALD3_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TALPID3 at Human |
| Immunogen: |
Synthesized peptide derived from human TALPID3 |
| Function | Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation. Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity. Required for asymmetrical localization of CEP120 to daughter centrioles. |
| Protein Name | Protein Talpid3 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomePhotoreceptor Inner SegmentCentrioleCilium Basal BodyForms A Ring-Like Structure At The Extreme Distal End Of Both Mother And Daughter CentriolesIn Photoreceptor Cells Localized To The Joint Between The Inner And Outer SegmentsSpecifically Localized At The Mother Centriole (Basal Body) And The Adjacent Centriole As Well As Between The Two Centrioles But Not In The Connecting Cilium |
| Alternative Antibody Names | Anti-Protein Talpid3 antibodyAnti-KIAA0586 antibodyAnti-TALPID3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
