Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root.not detected in any other tissues. |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
Protein Name | Keratin-Associated Protein 10-8High Sulfur Keratin-Associated Protein 10.8Keratin-Associated Protein 10.8Keratin-Associated Protein 18-8Keratin-Associated Protein 18.8 |
Database Links | Reactome: R-HSA-6805567 |
Alternative Antibody Names | Anti-Keratin-Associated Protein 10-8 antibodyAnti-High Sulfur Keratin-Associated Protein 10.8 antibodyAnti-Keratin-Associated Protein 10.8 antibodyAnti-Keratin-Associated Protein 18-8 antibodyAnti-Keratin-Associated Protein 18.8 antibodyAnti-KRTAP10-8 antibodyAnti-KAP10.8 antibodyAnti-KAP18-8 antibodyAnti-KRTAP10.8 antibodyAnti-KRTAP18-8 antibodyAnti-KRTAP18.8 antibody |
Information sourced from Uniprot.org