Anti-Keratin 8/18 antibody [B22.1/B23.1] (STJ180149)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k/IgG1k
ImmunogenCytokeratins purified from breast cancer MCF-7 cells
General Information
| Short Description | Mouse monoclonal Keratin 8/18 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | B22.1/B23.1 |
| Isotype | IgG1k/IgG1k |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100‐200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | KRT8KRT18 |
| Gene ID | 38563875 |
| Uniprot ID | K2C8_HUMANK1C18_HUMAN |
| Immunogen | Cytokeratins purified from breast cancer MCF-7 cells |
| Specificity | Positive control: Skin, breast carcinoma |
Additional Info
| Tissue Specificity | P05787 - Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.P05783 - Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 8 antibodyAnti-Cytokeratin-8 antibodyAnti-Ck-8 antibodyAnti-Keratin-8 antibodyAnti-K8 antibodyAnti-Type-Ii Keratin Kb8 antibodyAnti-KRT8 antibodyAnti-CYK8 antibodyAnti-Keratin - Type I Cytoskeletal 18 antibodyAnti-Cell Proliferation-Inducing Gene 46 Protein antibodyAnti-Cytokeratin-18 antibodyAnti-Ck-18 antibodyAnti-Keratin-18 antibodyAnti-K18 antibodyAnti-KRT18 antibodyAnti-CYK18 antibodyAnti-PIG46 antibody |
Information sourced from Uniprot.org