![Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149741/302485/STJ16101025_1__18791.1646940661.jpg?c=1 "Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)")
![Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149741/302485/STJ16101025_1__18791.1646940661.jpg?c=1 "Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)")
Anti-Keratin 19 antibody [EBS-IF-007] (STJ16101025)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenA BALB/c mouse was immunized with human breast cancer cell line MCF-7. Fusion Partner: P3-X63-Ag8.653.
General Information
| Short Description | Mouse monoclonal anti-Keratin 19 for use in FC, WB, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/WB/IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EBS-IF-007 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow Cytometry (1-2 µg/million cells in 0.1 ml, fix cells in 4% PFA for 10 min, at 4°C, permeabilize with 0, 2% saponin or digitonin for 15 min, at 4°C). Immunoblotting (1-2 µg/ml). Immunofluorescence (1-2 µg/ml). Immunohistology (formalin-fixed: 2-4 |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | KRT19 |
| Gene ID | 3880 |
| Uniprot ID | K1C19_HUMAN |
| Immunogen | A BALB/c mouse was immunized with human breast cancer cell line MCF-7. Fusion Partner: P3-X63-Ag8.653. |
Additional Info
| Tissue Specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. |
| Function | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Protein Name | Keratin - Type I Cytoskeletal 19Cytokeratin-19Ck-19Keratin-19K19 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 19 antibodyAnti-Cytokeratin-19 antibodyAnti-Ck-19 antibodyAnti-Keratin-19 antibodyAnti-K19 antibodyAnti-KRT19 antibody |
Information sourced from Uniprot.org