| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS). |
| Protein Name | Lysine-Specific Demethylase 4bJmjc Domain-Containing Histone Demethylation Protein 3bJumonji Domain-Containing Protein 2bHistone H3-Trimethyl-L-Lysine(9 Demethylase 4b |
| Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-5693565Reactome: R-HSA-9018519 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 4b antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 3b antibodyAnti-Jumonji Domain-Containing Protein 2b antibodyAnti-Histone H3-Trimethyl-L-Lysine(9 Demethylase 4b antibodyAnti-KDM4B antibodyAnti-JHDM3B antibodyAnti-JMJD2B antibodyAnti-KIAA0876 antibody |
Information sourced from Uniprot.org
