Western blot analysis of extracts of various cell lines, using KCNIP2 antibody (STJ29180) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-KCNIP2 antibody (1-90) (STJ29180)

SKU:
STJ29180
€140.63 - €655.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNIP2
Gene ID: 30819
Uniprot ID: KCIP2_HUMAN
Immunogen Region: 1-90
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human KCNIP2 (NP_775284.1).
Immunogen Sequence: MRGQGRKESLSDSRDLDGSY DQLTGHPPGPTKKALKQRFL KLLPCCGPQALPSVSENSVD DEFELSTVCHRPEGLEQLQE QTKFTRKELQ
Tissue Specificity Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
Post Translational Modifications Palmitoylated. Palmitoylation enhances association with the plasma membrane.
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart.
Protein Name A-Type Potassium Channel Modulatory Protein Kcnip2
Cardiac Voltage-Gated Potassium Channel Modulatory Subunit
Kv Channel-Interacting Protein 2
Kchip2
Potassium Channel-Interacting Protein 2
Database Links Reactome: R-HSA-5576894
Cellular Localisation Isoform 1: Cell Membrane
Lipid-Anchor
Detected On Lipid Rafts
Isoform 2: Cell Membrane
Isoform 6: Cell Membrane
Alternative Antibody Names Anti-A-Type Potassium Channel Modulatory Protein Kcnip2 antibody
Anti-Cardiac Voltage-Gated Potassium Channel Modulatory Subunit antibody
Anti-Kv Channel-Interacting Protein 2 antibody
Anti-Kchip2 antibody
Anti-Potassium Channel-Interacting Protein 2 antibody
Anti-KCNIP2 antibody
Anti-KCHIP2 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0008054 Anti-KCNIP2 antibody (STJA0008054) Rabbit Polyclonal Human/Mouse/Rat WB
STJ27861 Anti-SRSF3 antibody (1-90) (STJ27861) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/IF/ICC/ELISA
STJ26764 Anti-TIMM10 antibody (1-90) (STJ26764) Rabbit Polyclonal Human/Mouse/Rat WB/IF/ICC/ELISA
STJ119794 Anti-KLC2 antibody (1-90) (STJ119794) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ110522 Anti-MS4A12 antibody (1-90) (STJ110522) Rabbit Polyclonal Human WB/ELISA
STJ117451 Anti-ATP1A4 antibody (1-90) (STJ117451) Rabbit Polyclonal Mouse/Rat WB/ELISA
STJ117541 Anti-LIN7A antibody (1-90) (STJ117541) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ113634 Anti-KCNN1 antibody (1-90) (STJ113634) Rabbit Polyclonal Human/Mouse WB/ELISA
!