Anti-KCNH6 antibody (230-310 aa) (STJ191189)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 230-310
STJ191189
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General Information

Short DescriptionRabbit polyclonal anti-Potassium voltage-gated channel subfamily H member 6 (230-310 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolKCNH6
Gene ID81033
Uniprot IDKCNH6_HUMAN
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 230-310
Immunogen Region230-310 aa
SpecificityKCNH6 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Characterized by unusual gating kinetics by producing relatively small outward currents during membrane depolarization and large inward currents during subsequent repolarization which reflect a rapid inactivation during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization. Activates even more slowly than KCNH2.
Protein Name Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6
Ether-A-Go-Go-Related Gene Potassium Channel 2
Erg-2
Eag-Related Protein 2
Ether-A-Go-Go-Related Protein 2
Herg-2
Herg2
Potassium Voltage-Gated Channel Subfamily H Member 6
Voltage-Gated Potassium Channel Subunit Kv11.2
Database Links Reactome: R-HSA-1296072
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6 antibody
Anti-Ether-A-Go-Go-Related Gene Potassium Channel 2 antibody
Anti-Erg-2 antibody
Anti-Eag-Related Protein 2 antibody
Anti-Ether-A-Go-Go-Related Protein 2 antibody
Anti-Herg-2 antibody
Anti-Herg2 antibody
Anti-Potassium Voltage-Gated Channel Subfamily H Member 6 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv11.2 antibody
Anti-KCNH6 antibody
Anti-ERG2 antibody

Information sourced from Uniprot.org

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