• Immunofluorescence analysis of NIH/3T3 cells using JunB Rabbit polyclonal antibody (STJ27243) at dilution of 1:20 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-JUNB antibody (1-240) (STJ27243)

SKU:
STJ27243

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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-JUNB (1-240) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: JUNB
Gene ID: 3726
Uniprot ID: JUNB_HUMAN
Immunogen Region: 1-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human JunB (NP_002220.1).
Immunogen Sequence: MCTKMEQPFYHDDSYTATGY GRAPGGLSLHDYKLLKPSLA VNLADPYRSLKAPGARGPGP EGGGGGSYFSGQGSDTGASL KLASSELERLIVPNSNGVIT TTPTPPGQYFYPRGGGSGGG AGGAGGGVTEEQEGFADGFV KALDDLHKMNHVTPPNVSLG ATGGPPAGPGGVYAGPEPPP VYTNLSSYSPASASSGGAGA AVGTGSSYPTTTISYLPHAP PFAGGHPAQLGLGRGASTF
Post Translational Modifications Ubiquitinated by ITCH, leading to its degradation.
Function Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGAGCTCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity.
Protein Name Transcription Factor Junb
Transcription Factor Ap-1 Subunit Junb
Database Links Reactome: R-HSA-2173796
Reactome: R-HSA-6785807
Reactome: R-HSA-9031628
Reactome: R-HSA-9725371
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Junb antibody
Anti-Transcription Factor Ap-1 Subunit Junb antibody
Anti-JUNB antibody

Information sourced from Uniprot.org

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