Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-JUNB (1-240) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
JUNB |
Gene ID: |
3726 |
Uniprot ID: |
JUNB_HUMAN |
Immunogen Region: |
1-240 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human JunB (NP_002220.1). |
Immunogen Sequence: |
MCTKMEQPFYHDDSYTATGY GRAPGGLSLHDYKLLKPSLA VNLADPYRSLKAPGARGPGP EGGGGGSYFSGQGSDTGASL KLASSELERLIVPNSNGVIT TTPTPPGQYFYPRGGGSGGG AGGAGGGVTEEQEGFADGFV KALDDLHKMNHVTPPNVSLG ATGGPPAGPGGVYAGPEPPP VYTNLSSYSPASASSGGAGA AVGTGSSYPTTTISYLPHAP PFAGGHPAQLGLGRGASTF |
Post Translational Modifications | Ubiquitinated by ITCH, leading to its degradation. |
Function | Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGAGCTCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity. |
Protein Name | Transcription Factor JunbTranscription Factor Ap-1 Subunit Junb |
Database Links | Reactome: R-HSA-2173796Reactome: R-HSA-6785807Reactome: R-HSA-9031628Reactome: R-HSA-9725371 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Factor Junb antibodyAnti-Transcription Factor Ap-1 Subunit Junb antibodyAnti-JUNB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance