| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Jupiter Microtubule Associated Homolog 1 (50-154) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S5147RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JPT1 |
| Gene ID: |
51155 |
| Uniprot ID: |
JUPI1_HUMAN |
| Immunogen Region: |
50-154 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-154 of human HN1 (NP_057269.1). |
| Immunogen Sequence: |
NIFGTPEENQASWAKSAGAK SSGGREDLESSGLQRRNSSE ASSGDFLDLKGEGDIHENVD TDLPGSLGQSEEKPVPAAPV PSPVAPAPVPSRRNPPGGKS SLVLG |
| Tissue Specificity | Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta. |
| Function | Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteasomal degradation. |
| Protein Name | Jupiter Microtubule Associated Homolog 1Androgen-Regulated Protein 2Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Jupiter Microtubule Associated Homolog 1 antibodyAnti-Androgen-Regulated Protein 2 antibodyAnti-Hematological And Neurological Expressed 1 Protein Cleaved Into - Jupiter Microtubule Associated Homolog 1 - N-Terminally Processed antibodyAnti-JPT1 antibodyAnti-ARM2 antibodyAnti-HN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
