| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | JMJD4 |
| Gene ID: | 65094 |
| Uniprot ID: | JMJD4_HUMAN |
| Immunogen Region: | 1-463 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-463 of human JMJD4 (NP_075383.2). |
| Immunogen Sequence: | MRAGPEPQALAGQKRGALRL LVPRLVLTVSAPAEVRRRVL RPVLSWMDRETRALADSHFR GLGVDVPGVGQAPGRVAFVS EPGAFSYADFVRGFLLPNLP CVFSSAFTQGWGSRRRWVTP AGRPDFDHLLRTYGDVVVPV ANCGVQEYNSNPKEHMTLRD YITYWKEYIQAGYSSPRGCL YLKDWHLCRDFPVEDVFTLP VYFSSDWLNEFWDALDVDDY RFVYAGPAGSWSPFHADIF |
| Function | Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1. |
| Protein Name | 2-Oxoglutarate And Iron-Dependent Oxygenase Jmjd4Jmjc Domain-Containing Protein 4Jumonji Domain-Containing Protein 4Lysyl-Hydroxylase Jmjd4 |
| Database Links | Reactome: R-HSA-9629569 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-2-Oxoglutarate And Iron-Dependent Oxygenase Jmjd4 antibodyAnti-Jmjc Domain-Containing Protein 4 antibodyAnti-Jumonji Domain-Containing Protein 4 antibodyAnti-Lysyl-Hydroxylase Jmjd4 antibodyAnti-JMJD4 antibody |
Information sourced from Uniprot.org