| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-JDP2 (1-174) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JDP2 |
| Gene ID: |
122953 |
| Uniprot ID: |
JDP2_HUMAN |
| Immunogen Region: |
1-174 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human JDP2 (NP_001128521.1). |
| Immunogen Sequence: |
MVAGWPATPPAMMPGQIPDP SVTTGSLPGLGPLTGLPSSA LTVEELKYADIRNLGAMIAP LHFLEVKLGKRPQPVKSELD EEEERRKRRREKNKVAAARC RNKKKERTEFLQRESERLEL MNAELKTQIEELKQERQQLI LMLNRHRPTCIVRTDSVKTP ESEGNPLLEQLEKK |
| Post Translational Modifications | Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments. Polyubiquitinated.probably by IRF2BP1. |
| Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. |
| Protein Name | Jun Dimerization Protein 2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Jun Dimerization Protein 2 antibodyAnti-JDP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
