| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITPRIP |
| Gene ID: | 85450 |
| Uniprot ID: | IPRI_HUMAN |
| Immunogen Region: | 101-290 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-290 of human ITPRIP (NP_203755.1). |
| Immunogen Sequence: | EVWRQDHQEGPSPECLGGEE DELPGLGGAPLQGLTLPNKA TLGHFYERCIRGATADAART REFLEGFVDDLLEALRSLCN RDTDMEVEDFIGVDSMYENW QVDRPLLCHLFVPFTPPEPY RFHPELWCSGRSVPLDRQGY GQIKVVRADGDTLSCICGKT KLGEDMLCLLHGRNSMAPPC GDMENLLCAT |
| Tissue Specificity | Detected in brain where it is concentrated in cerebellar Purkinje cells (at protein level). |
| Function | Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release. |
| Protein Name | Inositol 1 -4 -5-Trisphosphate Receptor-Interacting ProteinProtein Danger |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus Outer Membrane |
| Alternative Antibody Names | Anti-Inositol 1 -4 -5-Trisphosphate Receptor-Interacting Protein antibodyAnti-Protein Danger antibodyAnti-ITPRIP antibodyAnti-DANGER antibodyAnti-KIAA1754 antibody |
Information sourced from Uniprot.org