Anti-ITPRIP antibody (101-290) (STJ113323)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ITPRIP (101-290) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ITPRIP |
| Gene ID | 85450 |
| Uniprot ID | IPRI_HUMAN |
| Immunogen Region | 101-290 |
| Immunogen Sequence | EVWRQDHQEGPSPECLGGEE DELPGLGGAPLQGLTLPNKA TLGHFYERCIRGATADAART REFLEGFVDDLLEALRSLCN RDTDMEVEDFIGVDSMYENW QVDRPLLCHLFVPFTPPEPY RFHPELWCSGRSVPLDRQGY GQIKVVRADGDTLSCICGKT KLGEDMLCLLHGRNSMAPPC GDMENLLCAT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 101-290 of human ITPRIP (NP_203755.1). |
Additional Info
| Tissue Specificity | Detected in brain where it is concentrated in cerebellar Purkinje cells (at protein level). |
| Function | Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release. |
| Protein Name | Inositol 1 -4 -5-Trisphosphate Receptor-Interacting ProteinProtein Danger |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus Outer Membrane |
| Alternative Antibody Names | Anti-Inositol 1 -4 -5-Trisphosphate Receptor-Interacting Protein antibodyAnti-Protein Danger antibodyAnti-ITPRIP antibodyAnti-DANGER antibodyAnti-KIAA1754 antibody |
Information sourced from Uniprot.org