| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-ITPR3 (Internal) is suitable for use in ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | ELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ITPR3 |
| Gene ID: | 3710 |
| Uniprot ID: | ITPR3_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002215.2 |
| Specificity: | No cross-reactivity expected with other types of ITPR |
| Immunogen Sequence: | DKKERPTDEEGFLH |
| Post Translational Modifications | Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues. |
| Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Involved in cellular calcium ion homeostasis. |
| Protein Name | Inositol 1 -4 -5-Trisphosphate Receptor Type 3Ip3 Receptor Isoform 3Ip3r 3Insp3r3Type 3 Inositol 1 -4 -5-Trisphosphate ReceptorType 3 Insp3 Receptor |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-1489509Reactome: R-HSA-2029485Reactome: R-HSA-2871809Reactome: R-HSA-381676Reactome: R-HSA-4086398Reactome: R-HSA-422356Reactome: R-HSA-5218921Reactome: R-HSA-5578775Reactome: R-HSA-5607763Reactome: R-HSA-9664323Reactome: R-HSA-9717207Reactome: R-HSA-983695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 3 antibodyAnti-Ip3 Receptor Isoform 3 antibodyAnti-Ip3r 3 antibodyAnti-Insp3r3 antibodyAnti-Type 3 Inositol 1 -4 -5-Trisphosphate Receptor antibodyAnti-Type 3 Insp3 Receptor antibodyAnti-ITPR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
