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Anti-ITPR2 antibody (2415-2480) (STJ11103923)

Immunofluorescence analysis of NIH/3T3 cells using ITPR2 Rabbit polyclonal antibody (STJ11103923) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
Immunohistochemistry analysis of ITPR2 in paraffin-embedded mouse kidney using ITPR2 Rabbit polyclonal antibody (STJ11103923) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
Immunohistochemistry analysis of ITPR2 in paraffin-embedded human liver using ITPR2 Rabbit polyclonal antibody (STJ11103923) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
Immunohistochemistry analysis of ITPR2 in paraffin-embedded rat lung using ITPR2 Rabbit polyclonal antibody (STJ11103923) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-ITPR2 antibody (2415-2480) (STJ11103923)

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STJ11103923

£112.50 - £522.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Inositol 1-4-5-Trisphosphate Receptor Type 2 (2415-2480) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ITPR2
Gene ID:	3709
Uniprot ID:	ITPR2_HUMAN
Immunogen Region:	2415-2480
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 2415-2480 of human ITPR2 (NP_002214.2).
Immunogen Sequence:	LFLKDDFTMEVDRLKNRTPV TGSHQVPTMTLTTMMEACAK ENCSPTIPASNTADEEYEDG IERTCD

Tissue Specificity	Isoform Short is found in skeletal muscle and heart.
Post Translational Modifications	Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
Function	Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
Protein Name	Inositol 1 -4 -5-Trisphosphate Receptor Type 2 Ip3 Receptor Isoform 2 Ip3r 2 Insp3r2 Type 2 Inositol 1 -4 -5-Trisphosphate Receptor Type 2 Insp3 Receptor
Database Links	Reactome: R-HSA-112043 Reactome: R-HSA-114508 Reactome: R-HSA-139853 Reactome: R-HSA-1489509 Reactome: R-HSA-2029485 Reactome: R-HSA-2871809 Reactome: R-HSA-381676 Reactome: R-HSA-4086398 Reactome: R-HSA-422356 Reactome: R-HSA-5218921 Reactome: R-HSA-5578775 Reactome: R-HSA-5607763 Reactome: R-HSA-9664323 Reactome: R-HSA-983695
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 2 antibody Anti-Ip3 Receptor Isoform 2 antibody Anti-Ip3r 2 antibody Anti-Insp3r2 antibody Anti-Type 2 Inositol 1 -4 -5-Trisphosphate Receptor antibody Anti-Type 2 Insp3 Receptor antibody Anti-ITPR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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