Anti-ITPR2 antibody (Internal) (STJ70839)

SKU:
STJ70839-100

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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ITPR2 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-3.75µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ITPR2
Gene ID: 3709
Uniprot ID: ITPR2_HUMAN
Immunogen Region: Internal
Accession Number: NP_002214.2
Specificity: No cross-reactivity expected with other types of ITPR.
Immunogen Sequence: PIEESNILSPVQD
Post Translational Modifications Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
Function Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
Protein Name Inositol 1 -4 -5-Trisphosphate Receptor Type 2
Ip3 Receptor Isoform 2
Ip3r 2
Insp3r2
Type 2 Inositol 1 -4 -5-Trisphosphate Receptor
Type 2 Insp3 Receptor
Database Links Reactome: R-HSA-112043
Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-1489509
Reactome: R-HSA-2029485
Reactome: R-HSA-2871809
Reactome: R-HSA-381676
Reactome: R-HSA-4086398
Reactome: R-HSA-422356
Reactome: R-HSA-5218921
Reactome: R-HSA-5578775
Reactome: R-HSA-5607763
Reactome: R-HSA-9664323
Reactome: R-HSA-983695
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 2 antibody
Anti-Ip3 Receptor Isoform 2 antibody
Anti-Ip3r 2 antibody
Anti-Insp3r2 antibody
Anti-Type 2 Inositol 1 -4 -5-Trisphosphate Receptor antibody
Anti-Type 2 Insp3 Receptor antibody
Anti-ITPR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance