| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITGAE |
| Gene ID: | 3682 |
| Uniprot ID: | ITAE_HUMAN |
| Immunogen Region: | 19-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3). |
| Immunogen Sequence: | FNVDVARPWLTPKGGAPFVL SSLLHQDPSTNQTWLLVTSP RTKRTPGPLHRCSLVQDEIL CHPVEHVPIPKGRHRGVTVV RSHHGVLICIQVLVRRPHSL SSELTGTCSLLGPDLRPQAQ ANFFDLENLLDPDARVDTGD CYSNKEGGGEDDVNTARQRR ALEKEEEEDKEEEEDEEEEE AG |
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Protein Name | Integrin Alpha-EHml-1 AntigenIntegrin Alpha-IelMucosal Lymphocyte 1 AntigenCd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain |
| Database Links | Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-E antibodyAnti-Hml-1 Antigen antibodyAnti-Integrin Alpha-Iel antibodyAnti-Mucosal Lymphocyte 1 Antigen antibodyAnti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibodyAnti-ITGAE antibody |
Information sourced from Uniprot.org