Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Isocitrate Dehydrogenenase 1 IDH1-R132H is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | HMab-1 |
Conjugation: | Unconjugated |
Isotype: | IgG1k |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | Lot specific |
Dilution Range: | IHC-P 1:25-1:50 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | KLH-conjugated peptide human IDH1 |
Background | Monoclonal Anti-IDH1 (R132H) recognizes only the R132H mutation of human IDH1 (R132H) and does not cross react with other mutations. The most frequent known mutation (>90%) is the alteration of arginine to histidine (R132H).6. Hence, antibodies that recognize the IDH1R132H mutation can be useful for the diagnosis of mutation-bearing tumors like gliomas. Positive control Human Glioma tissue |
Information sourced from Uniprot.org