| Short Description : | Mouse monoclonal anti-Isocitrate Dehydrogenenase 1 IDH1-R132H for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | HMab-1 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P 1:25-1:50 |
| Formulation: | Tissue culture supernatant with sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | KLH-conjugated peptide human IDH1 |
| Background | Monoclonal Anti-IDH1 (R132H) recognizes only the R132H mutation of human IDH1 (R132H) and does not cross react with other mutations. The most frequent known mutation (>90%) is the alteration of arginine to histidine (R132H).6. Hence, antibodies that recognize the IDH1R132H mutation can be useful for the diagnosis of mutation-bearing tumors like gliomas. Positive control Human Glioma tissue |
Information sourced from Uniprot.org

