| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-INTS10 (451-710) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INTS10 |
| Gene ID: |
55174 |
| Uniprot ID: |
INT10_HUMAN |
| Immunogen Region: |
451-710 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 451-710 of human INTS10 (NP_060612.2). |
| Immunogen Sequence: |
FLTDMIIYQGQYKKAIASLH HLAALQGSISQPQITGQGTL EHQRALIQLATCHFALGEYR MTCEKVLDLMCYMVLPIQDG GKSQEEPSKVKPKFRKGSDL KLLPCTSKAIMPYCLHLMLA CFKLRAFTDNRDDMALGHVI VLLQQEWPRGENLFLKAVNK ICQQGNFQYENFFNYVTNID MLEEFAYLRTQEGGKIHLEL LPNQGMLIKHHTVTRGITKG VKEDFRLAMERQVSRCGEN |
| Function | Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex. |
| Protein Name | Integrator Complex Subunit 10Int10 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Integrator Complex Subunit 10 antibodyAnti-Int10 antibodyAnti-INTS10 antibodyAnti-C8orf35 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
