| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-INPP5J (60-360) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INPP5J |
| Gene ID: |
27124 |
| Uniprot ID: |
PI5PA_HUMAN |
| Immunogen Region: |
60-360 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1). |
| Immunogen Sequence: |
VTWNVGTAMPPDDVTSLLHL GGGDDSDGADMIAIGLQEVN SMLNKRLKDALFTDQWSELF MDALGPFNFVLVSSVRMQGV ILLLFAKYYHLPFLRDVQTD CTRTGLGGYWGNKGGVSVRL AAFGHMLCFLNCHLPAHMDK AEQRKDNFQTILSLQQFQGP GAQGILDHDLVFWFGDLNFR IESYDLHFVKFAIDSDQLHQ LWEKDQLNMAKNTWPILKGF QEGPLNFAPTFKFDVGTNK |
| Function | Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles. |
| Protein Name | Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase AInositol Polyphosphate 5-Phosphatase JPhosphatidylinositol 1 -3 -4 -5-Tetrakisphosphate 5-PhosphatasePhosphatidylinositol 1 -4 -5-Trisphosphate 5-Phosphatase |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-1855183Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmPredominantly Localized To Membrane Ruffles |
| Alternative Antibody Names | Anti-Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase A antibodyAnti-Inositol Polyphosphate 5-Phosphatase J antibodyAnti-Phosphatidylinositol 1 -3 -4 -5-Tetrakisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol 1 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-INPP5J antibodyAnti-PIB5PA antibodyAnti-PIPP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
