Anti-INPP5E antibody (490-570 aa) (STJ190490)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 490-570
General Information
| Short Description | Rabbit polyclonal anti-Phosphatidylinositol polyphosphate 5-phosphatase type IV (490-570 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INPP5E |
| Gene ID | 56623 |
| Uniprot ID | INP5E_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 490-570 |
| Immunogen Region | 490-570 aa |
| Specificity | INP5E Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates. Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability. |
| Protein Name | Phosphatidylinositol Polyphosphate 5-Phosphatase Type Iv72 Kda Inositol Polyphosphate 5-PhosphataseInositol Polyphosphate-5-Phosphatase EPhosphatidylinositol 4 -5-Bisphosphate 5-PhosphatasePhosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase |
| Database Links | Reactome: R-HSA-1660514Reactome: R-HSA-5624958 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCytoplasmic SideCell MembraneCell ProjectionRuffleNucleusPeripheral Membrane Protein Associated With Golgi Stacks |
| Alternative Antibody Names | Anti-Phosphatidylinositol Polyphosphate 5-Phosphatase Type Iv antibodyAnti-72 Kda Inositol Polyphosphate 5-Phosphatase antibodyAnti-Inositol Polyphosphate-5-Phosphatase E antibodyAnti-Phosphatidylinositol 4 -5-Bisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-INPP5E antibody |
Information sourced from Uniprot.org