| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ING5 (1-220) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ING5 |
| Gene ID: |
84289 |
| Uniprot ID: |
ING5_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ING5 (NP_115705.2). |
| Immunogen Sequence: |
MATAMYLEHYLDSIENLPCE LQRNFQLMRELDQRTEDKKA EIDILAAEYISTVKTLSPDQ RVERLQKIQNAYSKCKEYSD DKVQLAMQTYEMVDKHIRRL DADLARFEADLKDKMEGSDF ESSGGRGLKKGRGQKEKRGS RGRGRRTSEEDTPKKKKHKG GSEFTDTILSVHPSDVLDMP VDPNEPTYCLCHQVSYGEMI GCDNPDCPIEWFHFACVDLT |
| Tissue Specificity | Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells. |
| Function | Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner. |
| Protein Name | Inhibitor Of Growth Protein 5P28ing5 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusChromosomeLocalizes To Transcription Start Sites |
| Alternative Antibody Names | Anti-Inhibitor Of Growth Protein 5 antibodyAnti-P28ing5 antibodyAnti-ING5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
