| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IMPA1 (1-277) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IMPA1 |
| Gene ID: |
3612 |
| Uniprot ID: |
IMPA1_HUMAN |
| Immunogen Region: |
1-277 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human IMPA1 (NP_005527.1). |
| Immunogen Sequence: |
MADPWQECMDYAVTLARQAG EVVCEAIKNEMNVMLKSSPV DLVTATDQKVEKMLISSIKE KYPSHSFIGEESVAAGEKSI LTDNPTWIIDPIDGTTNFVH RFPFVAVSIGFAVNKKIEFG VVYSCVEGKMYTARKGKGAF CNGQKLQVSQQEDITKSLLV TELGSSRTPETVRMVLSNME KLFCIPVHGIRSVGTAAVNM CLVATGGADAYYEMGIHCWD VAGAGIIVTEAGGVLMDVT |
| Function | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. |
| Protein Name | Inositol Monophosphatase 1Imp 1Impase 1D-Galactose 1-Phosphate PhosphataseInositol-1(Or 4-Monophosphatase 1Lithium-Sensitive Myo-Inositol Monophosphatase A1 |
| Database Links | Reactome: R-HSA-1855183 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Inositol Monophosphatase 1 antibodyAnti-Imp 1 antibodyAnti-Impase 1 antibodyAnti-D-Galactose 1-Phosphate Phosphatase antibodyAnti-Inositol-1(Or 4-Monophosphatase 1 antibodyAnti-Lithium-Sensitive Myo-Inositol Monophosphatase A1 antibodyAnti-IMPA1 antibodyAnti-IMPA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CLPP knockout (KO) 293T cells, using [KO Validated] CLPP Rabbit polyclonal antibody (STJ11100851) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89785/358257/STJ11100851_1__37533.1713122595.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CLPP knockout (KO) 293T cells, using [KO Validated] CLPP Rabbit polyclonal antibody (STJ11100851) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")