| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL21R |
| Gene ID: | 50615 |
| Uniprot ID: | IL21R_HUMAN |
| Immunogen Region: | 20-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4). |
| Immunogen Sequence: | GVSMPRGWAAPLLLLLLQGG WGCPDLVCYTDYLQTVICIL EMWNLHPSTLTLTWQDQYEE LKDEATSCSLHRSAHNATHA TYTCHMDVFHFMADDIFSVN ITDQSGNYSQECGSFLLAES IKPAPPFNVTVTFSGQYNIS WRSDYEDPAFYMLKGKLQYE LQYRNRGDPWAVSPRRKLIS VDSRSVSLLPLEFRKDSSYE LQVRAGPMPGSSYQGTWSEW S |
| Tissue Specificity | Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen. |
| Post Translational Modifications | C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame. |
| Function | This is a receptor for interleukin-21. |
| Protein Name | Interleukin-21 ReceptorIl-21 ReceptorIl-21rNovel Interleukin ReceptorCd Antigen Cd360 |
| Database Links | Reactome: R-HSA-9020958 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-21 Receptor antibodyAnti-Il-21 Receptor antibodyAnti-Il-21r antibodyAnti-Novel Interleukin Receptor antibodyAnti-Cd Antigen Cd360 antibodyAnti-IL21R antibodyAnti-NILR antibodyAnti-UNQ3121 antibodyAnti-PRO10273 antibody |
Information sourced from Uniprot.org
