• Confocal imaging of mouse tail ear using IL1RA Rabbit monoclonal antibody (STJ11101277, dilution 1:100) (Red). DAPI was used for nuclear staining (blue). Objective: 60x.
  • Confocal imaging of human skin using IL1RA Rabbit monoclonal antibody (STJ11101277, dilution 1:100) (Red). DAPI was used for nuclear staining (blue). Objective: 60x.
  • Western blot analysis of various lysates using IL1RA Rabbit monoclonal antibody (STJ11101277) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of various lysates using IL1RA Rabbit monoclonal antibody (STJ11101277) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-IL1RN antibody (100-177) [S7MR] (STJ11101277)

SKU:
STJ11101277

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-IL1RA (100-177) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL1RN
Gene ID: 3557
Uniprot ID: IL1RA_HUMAN
Immunogen Region: 100-177
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-177 of human IL1RA (NP_776214.1)
Immunogen Sequence: ETRLQLEAVNITDLSENRKQ DKRFAFIRSDSGPTTSFESA ACPGWFLCTAMEADQPVSLT NMPDEGVMVTKFYFQEDE
Tissue Specificity The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Function Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Protein Name Interleukin-1 Receptor Antagonist Protein
Il-1rn
Il-1ra
Irap
Icil-1ra
Il1 Inhibitor
Anakinra
Database Links Reactome: R-HSA-6783783
Reactome: R-HSA-9020702
Cellular Localisation Isoform 1: Secreted
Isoform 2: Cytoplasm
Isoform 3: Cytoplasm
Isoform 4: Cytoplasm
Alternative Antibody Names Anti-Interleukin-1 Receptor Antagonist Protein antibody
Anti-Il-1rn antibody
Anti-Il-1ra antibody
Anti-Irap antibody
Anti-Icil-1ra antibody
Anti-Il1 Inhibitor antibody
Anti-Anakinra antibody
Anti-IL1RN antibody
Anti-IL1F3 antibody
Anti-IL1RA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance