Anti-IL17RD antibody (STJ191859)

SKU:
STJ191859
$64.80 - $340.20
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Interleukin-17 receptor D is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL17RD
Gene ID: 54756
Uniprot ID: I17RD_HUMAN
Specificity: I17RD Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Might have a role in the early stages of fate specification of GnRH-secreting neurons. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Protein Name Interleukin-17 Receptor D
Il-17 Receptor D
Il-17rd
Il17rhom
Interleukin-17 Receptor-Like Protein
Sef Homolog
Hsef
Database Links Reactome: R-HSA-5674135
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Predominantly Associated With The Golgi Apparatus And Is Partially Translocated To The Plasma Membrane Upon Stimulation
Isoform 4: Cytoplasm
Alternative Antibody Names Anti-Interleukin-17 Receptor D antibody
Anti-Il-17 Receptor D antibody
Anti-Il-17rd antibody
Anti-Il17rhom antibody
Anti-Interleukin-17 Receptor-Like Protein antibody
Anti-Sef Homolog antibody
Anti-Hsef antibody
Anti-IL17RD antibody
Anti-IL17RLM antibody
Anti-SEF antibody
Anti-UNQ6115 antibody
Anti-PRO20026 antibody

Information sourced from Uniprot.org

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