Anti-IL-18BP antibody [R31-4Z-6] (STJA0035607)

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STJA0035607
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-IL-18BP for use in WB and IHC-P in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R31-4Z-6
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
IHC 1:100-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: IL18BP
Gene ID: 10068
Uniprot ID: I18BP_HUMAN
Immunogen: A synthesized peptide derived from human IL18 binding protein
Tissue Specificity Strongly expressed in heart, lung, placenta and spleen.
Post Translational Modifications N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4.
Function Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Protein Name Interleukin-18-Binding Protein
Il-18bp
Tadekinig-Alfa
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Secreted
Alternative Antibody Names Anti-Interleukin-18-Binding Protein antibody
Anti-Il-18bp antibody
Anti-Tadekinig-Alfa antibody
Anti-IL18BP antibody

Information sourced from Uniprot.org

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