Anti-IgG antibody [RWP49] (STJ16101822)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenProkaryotic recombinant protein corresponding to 327 amino acids of the human IgG molecule.
General Information
| Short Description | Mouse monoclonal anti-Immunoglobulin G for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RWP49 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | >=59 mg/L |
| Dilution Range | IHC-P 1:200 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8Β°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Prokaryotic recombinant protein corresponding to 327 amino acids of the human IgG molecule. |
Additional Info
| Background | The human immunoglobulins consist of two identical heavy chains (~50 kD) and two identical light chains, which are linked together by disulphide bonds. The light chains can be either kappa or lambda. The five immunoglobulins IgA, IgD, IgE, IgG and IgM differ in their heavy chains, and IgA and IgM differ as they can occur in polymeric forms. The heavy chain of IgG is named the gamma-chain. In humans, IgG consists of four sub classes that differ only marginally in their amino acid composition.Β Antibodies to IgG have been reported to be useful in the identification of plasma cells, lymphoid cells containing IgG and classifying B cell derived neoplasms. The normal B cell population is polyclonal, expressing a range of different immunoglobulins.Β In contrast, the majority of B cell neoplasms are characterized by the proliferation of monoclonal cells expressing one type of light chain, whereas more than one type of heavy chain can be expressed by the same cell.Β |
Information sourced from Uniprot.org