Anti-IAPP antibody [SAA0538] (STJA0019372)

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STJA0019372
£378.50 - £1,632.50
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Host: Mouse
Applications: ELISA/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Islet Amyloid Polypeptide is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : SAA0538
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: IAPP
Gene ID: 3375
Uniprot ID: IAPP_HUMAN
Function Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs.
Protein Name Islet Amyloid Polypeptide
Iapp
Amylin
Diabetes-Associated Peptide
Dap
Insulinoma Amyloid Peptide
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-418555
Reactome: R-HSA-419812
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Antibody Names Anti-Islet Amyloid Polypeptide antibody
Anti-Iapp antibody
Anti-Amylin antibody
Anti-Diabetes-Associated Peptide antibody
Anti-Dap antibody
Anti-Insulinoma Amyloid Peptide antibody
Anti-IAPP antibody

Information sourced from Uniprot.org