• Western blot analysis of A549 cells using SR-6 Polyclonal Antibody

Anti-HTR6 antibody (221-270 aa) (STJ95773)

SKU:
STJ95773

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 6 (221-270 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HTR6
Gene ID: 3362
Uniprot ID: 5HT6R_HUMAN
Immunogen Region: 221-270 aa
Specificity: SR-6 Polyclonal Antibody detects endogenous levels of SR-6 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human 5-HT-6 at the amino acid range 221-270
Function This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity. Is an activator of TOR signaling.
Protein Name 5-Hydroxytryptamine Receptor 6
5-Ht-6
5-Ht6
Serotonin Receptor 6
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 6 antibody
Anti-5-Ht-6 antibody
Anti-5-Ht6 antibody
Anti-Serotonin Receptor 6 antibody
Anti-HTR6 antibody

Information sourced from Uniprot.org

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