Anti-HTR3A antibody (24-484) (STJ27614)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HTR3A (24-484) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HTR3A |
| Gene ID | 3359 |
| Uniprot ID | 5HT3A_HUMAN |
| Immunogen Region | 24-484 |
| Immunogen Sequence | LAQGEARRSRNTTRPALLRL SDYLLTNYRKGVRPVRDWRK PTTVSIDVIVYAILNVDEKN QVLTTYIWYRQYWTDEFLQW NPEDFDNITKLSIPTDSIWV PDILINEFVDVGKSPNIPYV YIRHQGEVQNYKPLQVVTAC SLDIYNFPFDVQNCSLTFTS WLHTIQDINISLWRLPEKVK SDRSVFMNQGEWELLGVLPY FREFSMESSNYYAEMKFY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A (NP_000860.2). |
Additional Info
| Tissue Specificity | Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. |
| Function | Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. |
| Protein Name | 5-Hydroxytryptamine Receptor 3a5-Ht3-A5-Ht3a5-Hydroxytryptamine Receptor 35-Ht-35-Ht3rSerotonin Receptor 3aSerotonin-Gated Ion Channel Receptor |
| Database Links | Reactome: R-HSA-112314 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 3a antibodyAnti-5-Ht3-A antibodyAnti-5-Ht3a antibodyAnti-5-Hydroxytryptamine Receptor 3 antibodyAnti-5-Ht-3 antibodyAnti-5-Ht3r antibodyAnti-Serotonin Receptor 3a antibodyAnti-Serotonin-Gated Ion Channel Receptor antibodyAnti-HTR3A antibodyAnti-5HT3R antibodyAnti-HTR3 antibody |
Information sourced from Uniprot.org