• Western blot analysis of extracts of mouse lung, using HSP20/HSP20/HSPB6 antibody (STJ111929) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse lung, using HSP20/HSP20/HSPB6 antibody (STJ111929) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-HSPB6 antibody (1-160) (STJ111929)

SKU:
STJ111929

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HSPB6 (1-160) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSPB6
Gene ID: 126393
Uniprot ID: HSPB6_HUMAN
Immunogen Region: 1-160
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human HSP20/HSP20/HSPB6 (NP_653218.1).
Immunogen Sequence: MEIPVPVQPSWLRRASAPLP GLSAPGRLFDQRFGEGLLEA ELAALCPTTLAPYYLRAPSV ALPVAQVPTDPGHFSVLLDV KHFSPEEIAVKVVGEHVEVH ARHEERPDEHGFVAREFHRR YRLPPGVDPAAVTSALSPEG VLSIQAAPASAQAPPPAAAK
Post Translational Modifications The N-terminus is blocked. Phosphorylated at Ser-16 by PKA and probably PKD1K.required to protect cardiomyocytes from apoptosis.
Function Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
Protein Name Heat Shock Protein Beta-6
Hspb6
Heat Shock 20 Kda-Like Protein P20
Cellular Localisation Cytoplasm
Nucleus
Secreted
Translocates To Nuclear Foci During Heat Shock
Alternative Antibody Names Anti-Heat Shock Protein Beta-6 antibody
Anti-Hspb6 antibody
Anti-Heat Shock 20 Kda-Like Protein P20 antibody
Anti-HSPB6 antibody

Information sourced from Uniprot.org

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