Anti-HS2ST1 antibody (1-229) (STJ115778)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HS2ST1 (1-229) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HS2ST1 |
| Gene ID | 9653 |
| Uniprot ID | HS2ST_HUMAN |
| Immunogen Region | 1-229 |
| Immunogen Sequence | MGLLRIMMPPKLQLLAVVAF AVAMLFLENQIQKLEESRSK LERAIARHEVREIEQRHTMD GPRQDATLDEEEDMVIIYNR VPKTASTSFTNIAYDLCAKN KYHVLHINTTKNNPVMSLQD QVRFVKNITSWKEMKPGFYH GHVSYLDFAKFGVKKKPIYI NVIRDPIERLVSYYYFLRFG DDYRPGLRRRKQGDKKTFDE CVAEGGSDCAPEKLWLQIPF FCGHSSECW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human HS2ST1 (NP_001127964.1). |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the transfer of a sulfo group from 3'-phospho-5'-adenylyl sulfate (PAPS) to the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within the heparan sulfate (HS) chain and participates in HS biosynthesis. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. |
| Protein Name | Heparan Sulfate 2-O-Sulfotransferase 12-O-Sulfotransferase2-Ost2ostHs 2-O-SulfotransferaseHeparan Sulfate 2-Sulfotransferase |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Heparan Sulfate 2-O-Sulfotransferase 1 antibodyAnti-2-O-Sulfotransferase antibodyAnti-2-Ost antibodyAnti-2ost antibodyAnti-Hs 2-O-Sulfotransferase antibodyAnti-Heparan Sulfate 2-Sulfotransferase antibodyAnti-HS2ST1 antibodyAnti-HS2ST antibodyAnti-KIAA0448 antibody |
Information sourced from Uniprot.org