| Short Description : | Goat polyclonal antibody anti-HPS6 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 90-100kDa band observed in Human Lung and Human Skin lysates (calculated MW of 83.0kDa according to NP_079023). Recommended concentration: 1-3µg/ml. Primary incubation was for 1 |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HPS6 |
| Gene ID: | 79803 |
| Uniprot ID: | HPS6_HUMAN |
| Accession Number: | NP_079023 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | LRTELRDYRGLEC |
| Function | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. |
| Protein Name | Bloc-2 Complex Member Hps6Hermansky-Pudlak Syndrome 6 ProteinRuby-Eye Protein HomologRu |
| Cellular Localisation | Microsome MembraneCytoplasmCytosolEarly Endosome MembraneLysosome Membrane |
| Alternative Antibody Names | Anti-Bloc-2 Complex Member Hps6 antibodyAnti-Hermansky-Pudlak Syndrome 6 Protein antibodyAnti-Ruby-Eye Protein Homolog antibodyAnti-Ru antibodyAnti-HPS6 antibody |
Information sourced from Uniprot.org
