• Western blot analysis of lysates from HepG2, HeLa, and 293 cells, using HNF4 alpha/gamma Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using HNF-4 Alpha/Gamma Polyclonal Antibody

Anti-HNF-4 Alpha/Gamma antibody (91-140 aa) (STJ93555)

SKU:
STJ93555

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Hepatocyte nuclear factor 4-alpha and Hepatocyte nuclear factor 4-gamma (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HNF4A
HNF4G
Gene ID: 3172
3174
Uniprot ID: HNF4A_HUMAN
HNF4G_HUMAN
Immunogen Region: 91-140 aa
Specificity: HNF-4 Alpha/Gamma Polyclonal Antibody detects endogenous levels of HNF-4 Alpha/Gamma protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HNF4 alpha/gamma at the amino acid range 91-140
Function Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. Activates the transcription of CYP2C38. Represses the CLOCK-ARNTL/BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells.
Protein Name Hepatocyte Nuclear Factor 4-Alpha
Hnf-4-Alpha
Nuclear Receptor Subfamily 2 Group A Member 1
Transcription Factor 14
Tcf-14
Transcription Factor Hnf-4
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Hepatocyte Nuclear Factor 4-Alpha antibody
Anti-Hnf-4-Alpha antibody
Anti-Nuclear Receptor Subfamily 2 Group A Member 1 antibody
Anti-Transcription Factor 14 antibody
Anti-Tcf-14 antibody
Anti-Transcription Factor Hnf-4 antibody
Anti-HNF4A antibody
Anti-HNF4 antibody
Anti-NR2A1 antibody
Anti-TCF14 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance