| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-HMOX2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 37kDa band observed in lysates of cell line K562 (calculated MW of 36.0kDa according to NP_002125.3). Recommended concentration: 0.3-1µg/ml.IHC: In paraffin embedded Human |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HMOX2 |
| Gene ID: | 3163 |
| Uniprot ID: | HMOX2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002125.3 |
| Specificity: | Reported variants represent identical protein: NP_002125.3, NP_001120676.1, NP_001120678.1, NP_001120677.1 |
| Immunogen Sequence: | DQAGSTLARETLED |
| Function | Heme oxygenase 2: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Heme oxygenase 2 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. |
| Protein Name | Heme Oxygenase 2Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form |
| Database Links | Reactome: R-HSA-189483Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-917937Reactome: R-HSA-9707564 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic SideEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Heme Oxygenase 2 antibodyAnti-Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form antibodyAnti-HMOX2 antibodyAnti-HO2 antibody |
Information sourced from Uniprot.org
