• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HDAC10 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COS7 cells, using HDAC10 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Histone deacetylase 10 Polyclonal Antibody diluted at 1:1000

Anti-HDAC10 antibody (10-59 aa) (STJ93511)

SKU:
STJ93511

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Polyamine deacetylase HDAC10 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HDAC10
Gene ID: 83933
Uniprot ID: HDA10_HUMAN
Immunogen Region: 10-59 aa
Specificity: Histone deacetylase 10 Polyclonal Antibody detects endogenous levels of Histone deacetylase 10 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HDAC10 at the amino acid range 10-59
Function Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair.
Protein Name Polyamine Deacetylase Hdac10
Histone Deacetylase 10
Hd10
Database Links Reactome: R-HSA-2122947
Reactome: R-HSA-2644606
Reactome: R-HSA-2894862
Reactome: R-HSA-3214815
Reactome: R-HSA-350054
Cellular Localisation Cytoplasm
Nucleus
Excluded From Nucleoli
Alternative Antibody Names Anti-Polyamine Deacetylase Hdac10 antibody
Anti-Histone Deacetylase 10 antibody
Anti-Hd10 antibody
Anti-HDAC10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance