Anti-HIBCH antibody (33-330) (STJ11102854)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HIBCH (33-330) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HIBCH |
| Gene ID | 26275 |
| Uniprot ID | HIBCH_HUMAN |
| Immunogen Region | 33-330 |
| Immunogen Sequence | DAAEEVLLEKKGCTGVITLN RPKFLNALTLNMIRQIYPQL KKWEQDPETFLIIIKGAGGK AFCAGGDIRVISEAEKAKQK IAPVFFREEYMLNNAVGSCQ KPYVALIHGITMGGGVGLSV HGQFRVATEKCLFAMPETAI GLFPDVGGGYFLPRLQGKLG YFLALTGFRLKGRDVYRAGI ATHFVDSEKLAMLEEDLLAL KSPSKENIASVLENYHTESK IDRDKSFILEEHMDKINSC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 33-330 of human HIBCH (NP_055177.2). |
Additional Info
| Tissue Specificity | Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung. |
| Function | Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. |
| Protein Name | 3-Hydroxyisobutyryl-Coa Hydrolase - Mitochondrial3-Hydroxyisobutyryl-Coenzyme A HydrolaseHib-Coa HydrolaseHibyl-Coa-H |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9916722 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-3-Hydroxyisobutyryl-Coa Hydrolase - Mitochondrial antibodyAnti-3-Hydroxyisobutyryl-Coenzyme A Hydrolase antibodyAnti-Hib-Coa Hydrolase antibodyAnti-Hibyl-Coa-H antibodyAnti-HIBCH antibody |
Information sourced from Uniprot.org