Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-HEYL (1-100) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HEYL |
Gene ID: |
26508 |
Uniprot ID: |
HEYL_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HEYL (NP_055386.2). |
Immunogen Sequence: |
MKRPKEPSGSDGESDGPIDV GQEGQLSQMARPLSTPSSSQ MQARKKHRGIIEKRRRDRIN SSLSELRRLVPTAFEKQGSS KLEKAEVLQMTVDHLKMLHA |
Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. |
Protein Name | Hairy/Enhancer-Of-Split Related With Yrpw Motif-Like ProteinHheylClass B Basic Helix-Loop-Helix Protein 33Bhlhb33Hairy-Related Transcription Factor 3Hrt-3Hhrt3 |
Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-9013508Reactome: R-HSA-9762293 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Hairy/Enhancer-Of-Split Related With Yrpw Motif-Like Protein antibodyAnti-Hheyl antibodyAnti-Class B Basic Helix-Loop-Helix Protein 33 antibodyAnti-Bhlhb33 antibodyAnti-Hairy-Related Transcription Factor 3 antibodyAnti-Hrt-3 antibodyAnti-Hhrt3 antibodyAnti-HEYL antibodyAnti-BHLHB33 antibodyAnti-HRT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance