Anti-HEY2 antibody (17-32) (STJ117337)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HEY2 (17-32) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HEY2 |
| Gene ID | 23493 |
| Uniprot ID | HEY2_HUMAN |
| Immunogen Region | 17-32 |
| Immunogen Sequence | MKRPCEETTSESDMDETIDV GSENNYSGQSTSSVIRLNSP TTTSQIMARKKRRGIIEKRR RDRINNSLSELRRLVPTAFE KQGSAKLEKAEILQMTVDHL |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1). |
Additional Info
| Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. |
| Protein Name | Hairy/Enhancer-Of-Split Related With Yrpw Motif Protein 2Cardiovascular Helix-Loop-Helix Factor 1Hchf1Class B Basic Helix-Loop-Helix Protein 32Bhlhb32Hes-Related Repressor Protein 2Hairy And Enhancer Of Split-Related Protein 2Hesr-2Hairy-Related Transcription Factor 2Hrt-2Hhrt2Protein Gridlock Homolog |
| Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-8940973Reactome: R-HSA-9013508Reactome: R-HSA-9013695Reactome: R-HSA-9733709 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hairy/Enhancer-Of-Split Related With Yrpw Motif Protein 2 antibodyAnti-Cardiovascular Helix-Loop-Helix Factor 1 antibodyAnti-Hchf1 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 32 antibodyAnti-Bhlhb32 antibodyAnti-Hes-Related Repressor Protein 2 antibodyAnti-Hairy And Enhancer Of Split-Related Protein 2 antibodyAnti-Hesr-2 antibodyAnti-Hairy-Related Transcription Factor 2 antibodyAnti-Hrt-2 antibodyAnti-Hhrt2 antibodyAnti-Protein Gridlock Homolog antibodyAnti-HEY2 antibodyAnti-BHLHB32 antibodyAnti-CHF1 antibodyAnti-GRL antibodyAnti-HERP antibodyAnti-HERP1 antibodyAnti-HRT2 antibody |
Information sourced from Uniprot.org